ISCE Board of Directors

He has a BS degree in Biomedical engineering and MS degree in Electrical Engineer from Marquette University, He has over 40 years of experience in development of computerized ECG algorithms, ECG systems, clinical workflow solutions, user experience designs, and other cardiovascular technologies. He has held leadership roles across multiple teams and disciplines that are focused on advancement and innovation in the field of electrocardiology.

Brian has dedicated over 35 years of his career to the field of electrocardiography, starting with Marquette Electronics before it was acquired by General Electric. He has authored or co-authored many peer-reviewed publications and has been granted many international patents and has several still pending. He currently serves as Co-Chair of the AAMI ECG Committee, is a US National Expert on the ISO/IEC Joint Work Group 22 and is the AAMI Co-Chair of the US 62D Technical Advisory Group for Electromedical Equipment.

His research interests align at the intersection of cardiovascular sciences, biomedical modeling, and machine learning. Over the past 10 years, Dr. Al-Zaiti has contributed to the scientific investigation of more than dozen studies and has more than 100 scholarly publications. His current research at UPMC focuses on novel computational ECG markers of myocardial ischemia. Dr. Al-Zaiti currently serves as the principal investigator of an NHLBI-funded study to develop machine learning-based ECG methods that can detect biomarker evidence of non-ST elevation myocardial necrosis in patients with prehospital chest pain. On a parallel line of research, Dr. Al-Zaiti also aims to explore the role of ischemic preconditioning, apoptosis, and autophagy during acute myocardial injury.

In her current research, Dr. Zègre-Hemsey investigates cardiac monitoring, electrocardiography, other non-invasive physiological measures, and implementation of evidence-based innovations into prehospital and acute care settings to advance patient triage, diagnosis, and access to care.

Dr. Zègre-Hemsey is an emergency department nurse with a PhD in Nursing from the University of California, San Francisco. She is also an adult-gerontology clinical nurse specialist with a focus on critical-care trauma. Dr. Zègre-Hemsey holds an adjunct faculty appointment in the UNC School of Medicine, Department of Emergency Medicine.

He has graduated as an Electrical Engineer from the Swiss Federal Institute of Technology Lausanne while doing exchange studies at the Georgia Institute of Technology and University College of Dublin. He got his PhD from the Department of Radiology at the Centre Hospitalier Universitaire de Nancy and from the National Polytechnic Institute of Lorraine, Nancy in France.

His work has been recognized with national and international awards. He has published more than 30 peer-reviewed scientific articles, holds nine patents, and helped developing several medical devices in different field of MedTech including the field of electrocardiology. He is a specialist in the new European Medical Device Regulation related to product development especially in high-end signal processing such as AI/ML.

In 1994, he received doctoral degree in Electrical Engineering from the University of Rochester, NY. Since 1998 he is involved in the pharmaceutical industry arena and he is founder and president of AMPS-LLC, NY, a company tailoring software-oriented solutions involving analysis of biomedical signals. AMPS software tools are used today by most ECG core laboratories and by many academic institutions.

Dr. Badilini participated to the development of the HL7 ECG standard. In 2009, Dr Badilini received an Honorary Fellowship from the American College of Cardiology for his “Contributions to the field of non-invasive electrocardiology”. Since 2018, Dr. Badilini is a full professor at the University of California of San Francisco where he directs the Center for Physiologic Research.

An ICU nurse by background, she earned a BS in nursing from the University of Buffalo and a MS and PhD in nursing from the University of California San Francisco. Carey is a highly respected researcher whose work has made significant contributions to the understanding of the electrocardiogram.

With National Institutes of Health funding, she has improved the detection of myocardial ischemia in adults with and without heart disease. A prolific scientific writer, Dr. Carey has authored nearly 250 peer-reviewed and scholarly articles; plus, book chapters. She is also a professional scientific speaker and has earned numerous honors in her 30-year career.

During his 30 year tenure, Johan has contributed to many developments and validation efforts in the company, and authored or co-authored numerous publications, often in cooperation with scientific institutions. He coached numerous students from the University of Bologna during his time at Mortara and co-hosted the 2008 edition of the annual “Computing in Cardiology” conference in Bologna, Italy.

His specialties are clinical use cases of ECG’s, ECG and vital signs monitoring, ECG-related algorithm development, Device-Human Interfaces and Usability, Medical Device standards and Risk Analysis, Project management, Technical Communication, Healthcare and Drug Trial Workflows.

With a background in biomedical engineering and a PhD from Aalborg University in 2010, he has devoted his career to advancing the clinical and scientific utility of the ECG — from basic signal analysis to national-scale cardiac epidemiology and regulatory-grade digital biomarkers.

He has contributed to advancing methods for detecting clinically manifest and subclinical forms of atrial fibrillation, quantifying electrical dyssynchrony in the heart, assessing cardiotoxicity, and identifying individuals at risk of sudden cardiac death. At ISCE, Professor Graff is committed to fostering global exchange of ideas, mentoring young scientists, and advancing innovation at the intersection of cardiology and computational science.

He received the MD degree in 1978 from the University of Mississippi and trained in Internal Medicine and Cardiology at Duke University. In 2017, he became the inaugural director of the UVa Center for Advanced Medical Analytics Engineering.

He has published about 200 full-length peer-reviewed papers in journals including Nature, Science, Physical Review Letters, Journal of Clinical Investigation, Journal of General Physiology, Biophysical Journal, Circulation, Circulation Research, and Critical Care Medicine. He is currently a Principal Investigator on three NIH grants.

He began his career developing intelligent control systems for commercial printing presses, designing optics, electronics, and image processing algorithms to overcome engineering challenges in harsh environments. In 2014, he joined Mortara Instrument, Inc. where he designed embedded software and algorithms for electrocardiograph devices, and helped develop international safety standards as a member of the AAMI/EC ECG committee.

Patrick received a B.S. in physics and mathematics from Carroll College in 1995 and is currently pursuing a Ph.D. in biomedical engineering from Marquette University and the Medical College of Wisconsin, with a focus on computational electrophysiology modeling of the fetal ventricular cardiomyocyte.

From 2010 to 2011, Ramun worked at the Institute for Communication Systems in Rapperswil, before joining Schiller AG in Baar, Switzerland. Over the years, he has developed deep expertise in ECG signal processing, contributing to advancements in filtering techniques, data-driven interpretation algorithms, and non-invasive blood pressure analysis.

Currently, Ramun leads the algorithm development team at Schiller AG, where he manages projects in cooperation with academic and clinical partners. In parallel with his industry role, Ramun serves as a lecturer in biosignal processing at the Lucerne University of Applied Sciences and Arts.

He is faculty in the Joint UC Berkeley/UCSF Computational Precision Health Program. He is a practicing cardiologist and leads a computational research lab at UCSF focused on cardiovascular disease phenotyping and prediction using artificial intelligence and epidemiologic methods. He received the DP2 New Innovator Award from the National Institutes of Health Office of the Director, and his work has been supported by the National Institutes of Health, the Patient-Centered Outcomes Research Institute among others.

During his 30 year tenure, Johan has contributed to many developments and validation efforts in the company, and authored or co-authored numerous publications, often in cooperation with scientific institutions. He coached numerous students from the University of Bologna during his time at Mortara and co-hosted the 2008 edition of the annual “Computing in Cardiology” conference in Bologna, Italy.

His specialties are clinical use cases of ECG’s, ECG and vital signs monitoring, ECG-related algorithm development, Device-Human Interfaces and Usability, Medical Device standards and Risk Analysis, Project management, Technical Communication, Healthcare and Drug Trial Workflows.

He also holds adjunct faculty appointments in the Department of Computer Science and the Department of Biomedical Engineering through Emory University and the Georgia Institute of Technology. His research focuses on advancing cardiovascular care using physiological signal processing and AI/machine learning, with particular emphasis on the early recognition of acute coronary artery occlusion and cardiovascular risk assessment.