ISCE 2004 Sessions and Poster Session Speakers

Session I

QT Prolonging Drugs - Basic, Clinical and Regulatory Issues

Session Chair

Charles Antzelevitch, PhD
Masonic Medical Research Laboratory
Utica, NY USA

Session Co-Chair
Justin Mortara
Mortara Instrument, Inc.
Milwaukee WI USA

Konrad Brockmeier, University of Köln, Köln GERMANY
Chair's Welcome & Opening Remarks

Justin Mortara, Mortara Instrument, Inc., Milwaukee WI USA
Defining the Problem, Its Clinical Scope and Impact

Michael J. Ackerman, Mayo Clinic, Kalamazoo M IUSA
Genetic and Molecular Basis for Congenital and Acquired LQTS

Gan-Xin Yan, Main Line Health Heart Center, Lankenau Medical Center, Wynnewood PA USA
Preclinical Strategies to Assess QT Liability and Torsadogenic Potential of New Drugs: The Role of Experimental Models

Charles Antzelevitch, Masonic Medical Research Laboratory, Utica NY USA
Is QT Prolongation Really The Problem?

Marek Malik, St. George's Hospital Medical School, London, UNITED KINGDOM
Assessing Patient-Specific Risks. Problems Associated With Measurement and Rate Correction of Repolarization Parameters

Luiz Belardinelli, CV Therapeutics, Palo Alto, CA
A Mechanistic Approach to Assess Proarrhythmic Risk of QT-Prolonging Drugs: A Pharmaceutical Industry Perspective

Norman L. Stockbridge, US Food & Drug Administration, Rockville MD USA
Regulatory Issues: The Quandary Facing the FDA. Concept Paper and S7B

Poster Session 1

John Madias, Mount Sinai School of Medicine, Elmhurst NY USA
Augmentation of the Amplitude of QRS Complexes in Patients with Heart Failure Treated with Diuresis for 48 Hours

John Madias, Mount Sinai School of Medicine, Elmhurst NY USA
Anasarca Peripheral Edema of Varying Etiology Conceals the ECG Diagnosis of Left Ventricular Hypertrophy

Henk Ritsema van Eck, Erasmus Medical College, Rotterdam THE NETHERLANDS
Genesis of the Normal T-U Wave: A Slice Model of the Left Ventricular Myocardium

Claire Sommargren, University of CA San Francisco, San Francisco CA USA
Electrocardiographic Abnormalities in Patients with Subarachnoid Hemorrhage and Normal Adults: A Comparison Study

David Tong, Southwest Research Institute, San Antonio TX USA
Using Motion Sensors to Reduce Motion Artifact in the ECG

Shu-Fen Wung, University of Arizona, Tucson AZ USA
What Are the Implications for Using Modified (Mason-Likar) Exercise Lead System in Research?

Session II

Atrial Fibrillation

Session Chair
Wolfgang Schoels
University of Heidelberg
Heidelberg GERMANY

Session Co-Chair
Arne Sippens Groenewegen
Heart Center for Excellence
Kalamazoo MI USA

Wolfgang Schoels, University of Heidelberg, Heidelberg GERMANY
Overview

Gil Bub, McGill University, Toronto CANADA
A Cell Culture Model of Paroxysmal Atrial Fibrillation

Arne Sippens Groenewegen, Heart Center for Excellence, Kalamazoo MI USA
Potential Role of Body Surface ECG Mapping for Localization of AF Trigger Sites

Hans-Jürgen Wildau, BIOTRONIK GmbH & Co. KG, Berlin GERMANY
Wireless Remote Monitoring in Patients with Atrial Tachyarrhythmias

Wolfgang Schoels, University of Heidelberg, Heidelberg, GERMANY
Catheter Ablation of Atrial Fibrillation: Navigation Tools and Energy Sources

David Ritscher, Medtronic, Inc., Minneapolis MN USA
Implantable Device Based Therapy for Management of AF

Session III

Regulatory Issues, Home Monitoring, FDA and Manufacturer Interaction

Session Chair
Mitchell Krucoff
Duke University Medical Center
Durham NC USA

Session Co-Chair
Charles Ho
US FDA
Rockville MD USA

Mitchell Krucoff, Duke University Medical Center, Durham NC USA
Overview

Norman Stockbridge, U.S. Food and Drug Administration, Rockville MD USA
Electronic Waveform Format for ECG Safety Data Supporting IND Submissions

Justin Mortara, Mortara Instrument, Inc. Milwaukee WI USA
Comparison of European and U.S. Regulation of Computerized ECG Devices

Charles Ho, U.S. Food and Drug Administration, Rockville MD USA
Computerized ECG Tool Claims and Clinical Claims

Mitchell W. Krucoff, Duke University Medical Center, Durham NC USA
Permanently Implantable Diagnostic and Therapeutic Computerized ECG Devices: Where Is the Regulatory Bar?

James J. Bailey, National Institutes of Health, Bethesda MD USA
The Triangular Wave Test for Electrocardiographics

Elias Mallis, U.S. Food and Drug Administration, Rockville MD USA
Home Monitoring Systems: Regulatory Challenges

Poster Session 2

Ljuba Bacharova, International Laser Center, Bratislava SLOVAK REPUBLIC
Changes in QRS Amplitude and Left Ventricular Mass in Rats Treated by Enalapril and Lacidipine

Amir Beker, Biological Signal Processing, Tel Aviv ISRAEL
High Frequency Mid-QRS Potentials During Treadmill Ergometry in Cases of Inconclusive ST-based Diagnosis

Pamela Douglas, Nat'l. Space Biomedical Research Institute, Philadelphia PA USA
Temporal and Postural Variation of 12-Lead High Frequency QRS ECG Signals

Richard Gregg, Philips Medical Systems, Andover MA USA
Automatic Discrimination of Atrial Flutter from Other Supraventricular Rhythms by Autocorrelation and Power Spectral Analysis

Medit Jumabay, Nihon University School of Medicine, Tokyo JAPAN
Cardiac Autonomic Control in Warm-up Phenomenon - Analysis of Heart Rate Variability during Repeated Treadmill Exercise Testing in Patients with Stable Effort Angina Using the New Developed Wavelet Method

Chun-Cheng Lin, Nat'l. Taiwan University of Science & Technology, Hsinchu TAIWAN
Late Potential Segment Selection for Frequency-Domain SAECG Analysis

Chun-Cheng Lin, Nat'l. Taiwan University of Science & Technology, Hsinchu TAIWAN
Effects of Age, Gender and Race on Time-Domain SAECG

Robert Lux, University of Utah, Salt Lake City UT USA
New Leads for P Wave Detection and Arrhythmia Classification

Session IV

Presentations from Submitted Abstracts

Session Chair
Peter Clemmensen
Copenhagen University Hospital
Copenhagen DENMARK

Session Co-Chair
Ljuba Bacharova
International Laser Center
Bratislava SLOVAK REPUBLIC

Peter Clemmensen, Copenhagen University Hospital, Copenhagen DENMARK
Overview

Shen Luo
A Comparison of Commonly Used QT Correction Formulae

Peter Macfarlane
Modification of ACC/ESC Criteria for Acute Myocardial Infarction

Jason Ng
Surface ECG Vector Characteristics of Organized and Disorganized Atrial Activity During Atrial Fibrillation

Esther Pueyo
A Combined Methodology to Accurately Determine QT Interval Limits

Sophia Zhou
Normal ECG Limits in Asian Children

Session V

Novel Cardiac Mapping, New Devices in Cardiac Data Acquisition

Session Chair
Juergen Hescheler
University of Köln
Köln GERMANY

Session Co-Chair
Robert Lux
University of Utah CVRTI
Salt Lake City UT USA

Juergen Hescheler, University of Köln, Köln GERMANY
Overview

Michael Reppel, University of Köln, Köln GERMANY
Multi-Electrode-Arrays (MEAs): A New Tool to Measure Embryonic Heart Activity

Juergen Hescheler, University of Köln, Köln GERMANY
Characterisation of the Embryonic Heart and ES Cell Derived Cardiomyocytes Using MEAs

Hans Koch, Physikalisch-Technische Bundesanstalt, Berlin GERMANY
Recent Advances in Magnetocardiography

Rodrigo Weber dos Santos, Physikalisch Technische Bundesanstalt, Berlin GERMANY
MCG to ECG Source Differences: A 2D Computer Model Study

Bonnie B. Punske, CVRTI University of Utah, Salt Lake City, UT USA
Optical Mapping of Propagation Changes Induced by Elevated Extracellular Potassium in Mouse Hearts

Emilio Macchi, Universita degli Studi, Parma ITALY
Impulse Initiation in Cardiac Muscle with Special Attention to the Structure-Function Relationship

Poster Session 3

Camilo Bruce, Inovise Medical, Inc., Newberg OR USA
A Gender Comparison of Electrocardiographic Findings in Patients with Acute Myocardial Infarction Who Did Not Receive an Acute Intervention

Dewar Finlay, University of Ulster, Newtownabbey NORTHERN IRELAND
Visualisation of Body Surface Electrocardiographic Features in Myocardial Infarction

B. Milan Horacek, Dalhousie University, Halifax NS CANADA
Comparative Ability of Standard 12-Lead ECG and of Simpler Alternative Systems to Detect Acute Myocardial Ischemia

Charles W. Olson, ECG-TECH CORP., Huntington NY USA
Detection of Ischemia Using ST and T-wave Vector Magnitude and Angle Characteristics That Reject Body Positional Change Effects

Colum Owens
Right Ventricular Infarction Complicating Inferior Myocardial Infarction Correlates with Higher TIMI Risk Scores and Increased In-Hospital Morbidity and Mortality

Maria Sejersten, Duke University, Copenhagen DENMARK
Detection Of Acute Ischemia from 12-Lead ECGs Derived from EASI Leads and from 12-Lead ECGs Acquired in Clinical Practice

Martin Sillesen, Copenhagen University, Copenhagen DENMARK
Telemedical Transmission of Prehospital ECGs in Patients with Acute Chest Pain

Bob Warner, Inovise Medical, Inc., Newberg OR USA
Comparing the ECG and the Fourth Heart Sound for Detecting Acute MI

Session VI

Jos Willems Young Investigators Competition

Session Chair
Janice Jenkins
University of Michigan
Ann Arbor MI USA

Session Co-Chair
Yuji Kasamaki
Nihon University School of Medicine
Tokyo, JAPAN

Janice Jenkins, University of Michigan, Ann Arbor MI USA
Overview

Markus Khalil, University of Heidelberg, Heidelberg GERMANY
Sympathovagal Imbalance in Pediatric Patients with Neurocardiogenic Syncope during Asymptomatic Time Periods

Stefan P. Nelwan, Erasmus Medical College, Rotterdam THE NETHERLANDS
Simultaneous Comparison of Three Derived 12-lead ECGs with Standard ECG at Rest and during Percutaneous Coronary Occlusion

Rasmus Ripa, Rigshospitalet, Copenhagen DENMARK
Time to Treatment Has Little Influence on Myocardial Salvage after AMI: A DANAMI-2 Substudy

Zhendong Song, Illinois Institute of Technology, Chicago IL USA
Feasibility of Ischemia Detection in a Subcutaneous Monitor

Session VII

Mining for Information in Ventricular Repolarization: What Is the Profit?

Session Chair
Jan Kors
Erasmus Medical College
Rotterdam THE NETHERLANDS

Session Co-Chair
Paul Kligfield
Cornell University Medical College
New York, NY USA

Jan Kors, Erasmus Medical College, Rotterdam THE NETHERLANDS
Overview

Vladimir Shusterman, University of Pittsburgh, Pittsburgh PA USA
Tracking Repolarization Dynamics in Real-Life Data

Adriaan van Oosterom, Ecole Polytechnique Federale, Lausanne SWITZERLAND
The Dominant T Wave

Uwe Steinhoff, Physikalisch-Technische Bundesanstalt, Berlin GERMANY
Screening for Safety Pharmacology Studies with High Through-Put and Reliability by Utilizing Magnetocardiography

Jan A. Kors, Erasmus Medical College, Rotterdam THE NETHERLANDS
Spatial Repolarization Parameters for Predicting Cardiac Death in the Elderly

Marek Malik, St. George's Hospital Medical School, London ENGLAND
T-wave morphology and its clinical utility

Peter Macfarlane, Royal Infirmary, Glasgow SCOTLAND
Looking for Prognostic Information in the ST-T Segment - Is It Really Worth It?

Session VIII

Prehospital Decision Making

Session Chair
Barbara Drew
University of California San Francisco
San Francisco CA USA

Session Co-Chair
David Hampton
Medtronic Physio-Control
Redmond WA USA

Barbara Drew, University of California San Francisco, San Francisco, CA USA
Overview

Barbara Drew, University of California San Francisco, San Francisco, CA USA
Tele-electrocardiography in Acute Coronary Syndromes: Preliminary Results of the ST SMART Study

Peter Clemmensen, Copenhagen University Hospital, Copenhagen DENMARK
Pre-hospital Diversion to Hospital with PCI using Wireless 12-Lead ECG Transmission

Colum Owens, Regional Medical Cardiology Centre, Belfast NORTHERN IRELAND
Pre-hospital 80-Lead Mapping: Does it Add Significantly to the Diagnosis of Acute Coronary Syndromes?

Joel Q. Xue, GE Medical Systems, Menomonee Falls WI USA
Added Value of New ACS Algorithm for Better Interpretation Accuracy of Pre-Hospital ECGs

Robert Lux, University of Utah, Salt Lake City UT USA
Initial Non-Diagnostic ECG in Acute MI: Can Estimated Body Surface Potential Maps Help?



   
                 
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